HIV Epidemiology, Surveillance and Threat Assessment

Recent Advances

In 2006, scientists characterized new circulating recombinant forms in East Asia and documented dual infection and super infection from different HIV subtypes. In addition, program scientists documented that many recombinant strains are generated within high-risk social networks, with high rates of transmission. These high-risk social networks can be the initial amplifier of new recombinants.

USMHRP threat assessment and global molecular epidemiology activities are aimed at tracking the HIV epidemic in active duty forces and assessing the risk of HIV exposure to U.S. and allied forces deployed overseas.

Military Risk Assessment

The U.S. military continues to deploy around the globe. The core concern remains providing up-to-date information concerning the risk of HIV exposure in areas of current deployments and in areas of instability where future deployments may occur, the safety of the local, in-country (non-U.S.) blood supply, the potential for allied troop (Central and Eastern Europe and Central Asia) mass casualty exposure and risk to health care personnel in theater.

Another critical aspect of this mission is the continued assessment of the HIV-1 subtypes infecting the active force, especially during overseas deployments and operations, as well as the assessment of the subtypes affecting young, civilian applicants for military service.

In addition to Africa and Thailand, USMHRP assesses the HIV threat to U.S. military forces in the former Soviet Union and in Eastern Europe/Central Asia, South America and the Caribbean.

Identifying High Incidence Areas

Studies of the HIV epidemic in areas of potential troop deployment overseas often help identify high incidence areas that may be suitable for vaccine clinical trials. These surveillance activities can then lay the groundwork for building a vaccine trial site. This includes developing laboratory capability, identifying reliable and capable professional colleagues and developing a familiarity with the host government and its regulations.

USMHRP International Network:
Nigeria | Kenya | Tanzania | Uganda | Thailand