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March 24, 2017
World TB Day: MHRP Research Physician Focuses on Problem of TB/HIV Co-infection

HIV and tuberculosis (TB) are a deadly combination.  TB is the leading cause of death among individuals living with HIV, accounting for 25% of HIV-related deaths among HIV positive people.

TB is an opportunistic infection that more easily takes hold in individuals with weakened immune systems. An individual living with HIV is 20 to 30 times more likely to develop TB than an uninfected...

March 23, 2017
New Multi-site Phase 2 Ebola Vaccine Study Begins in Africa

The U.S. Military HIV Research Program (MHRP) at the Walter Reed Army Institute of Research (WRAIR) initiated a Phase 2 clinical trial to evaluate the safety and immunogenicity of a prime-boost Ebola vaccine regimen in both healthy and HIV-infected volunteers. The multisite study began today with its first vaccination in Uganda. The trial will also take place in Nigeria, Kenya, Tanzania and...

February 16, 2017
Insight into Acute HIV Infection

MHRP's HIV acute cohorts, RV217 and RV254, provide insight into crucial stages of early HIV infection. The acute, or first stage of HIV infection immediately follows exposure to the virus and occurs before common tests to diagnosis HIV are able to identify infection. It is during this stage that the virus begins to replicate and invade the immune system. 

In Thailand, MHRP researchers...

February 15, 2017
New Study Provides Clues to Early T Cell Immune Responses in Acute HIV Infection

A new study has shown that potent HIV-specific CD8+ T cells that are able to kill HIV-producing cells and reduce the seeding of the HIV reservoir are only detected at peak viremia in acute HIV infection. Findings from the study, which was led by MHRP, were published today in Science Translational Medicine.

HIV-specific CD8+ T cells are white blood cells that kill cells infected with HIV...

February 10, 2017
MHRP Researchers and Collaborators Presenting at CROI 2017

MHRP and collaborators are scheduled to speak and present at CROI 2017, taking place February 13-16 in Seattle.

Dr. Jintanat Ananworanich, MHRP’s Associate Director for Therapeutics Research, will present during the first plenary of the conference on Tuesday, February 14, a talk titled, “The Emerging Potential for HIV Cure for Infants, Children, and Adults.”

Other MHRP...

February 6, 2017
Col. Nelson Michael Selected as One of Vice Motherboard’s ‘Humans of the Year’

Online science and tech magazine Motherboard has selected MHRP’s director Col. Nelson Michael as a "Human of the Year" for his work developing vaccines for HIV and other emerging diseases, namely Ebola and Zika.

In their selection, Motherboard aimed to “focus on a few enterprising individuals in science and tech in particular — people whose names you may not recognize right away, but...

January 11, 2017
U.S. Officials Visit with Participants in DREAMS Program

U.S. Ambassador to Uganda Deborah R. Malac and Deputy Assistant Secretary of State for Africa Dr. Shannon Smith earlier this month visited a group of girls and young women participating in the DREAMS program at a Makerere University Walter Reed Project (MUWRP) site in the Mukono District of Uganda.

The President’s Emergency Plan for Aids Relief (PEPFAR) last year initiated the DREAMS...

January 10, 2017
Nigeria Study Identifies Potential Cohorts for HIV Vaccine Development

A recently-published study conducted by researchers from the U.S. Military HIV Research Program (MHRP) found that high HIV-1 prevalence in two communities in Nigeria, along with a reported high-level of willingness to participate in future HIV intervention studies, indicate favorable epidemiological and logistic conditions for cohort development for HIV vaccine studies in the region.

...

December 21, 2016
Dr. Lydie Trautmann Awarded R01 Grant from National Institute of Mental Health

Dr. Lydie Trautmann, chief of the cellular immunology lab section for the U.S. Military HIV Research Program (MHRP), and her colleagues from Yale, University of Hawaii and SEARCH Thailand have won a $2.6 million (total over 5 years) grant from the National Institute of Mental Health for a project on the critical role of cytotoxic T cells in HIV neuropathogenesis. 

Dr. Trautmann will be...

December 15, 2016
Koome Island Demonstration Farm Helps Support Women and Families

A group of mothers from several of the Koome Islands of Uganda have come together with the support of the Makerere University Walter Reed Project (MUWRP) to build and work a demonstration farm, a project meant to provide stability, teach vocational skills and bring additional income to this traditionally migratory and vulnerable population.

Through outreach efforts, MUWRP found out that...

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