Dr. Denise Hsu is a Research Physician and the Associate Director of Therapeutics at the U.S. Military HIV Research Program (MHRP). She was previously the Head of the Nonhuman primate lab, Department of Retrovirology, AFRIMS. Her current research involves laboratory bench work, animal studies and clinical trials. Her interests include delineating the sources of HIV persistence, assessing various HIV cure interventions as well as investigating the impact of HIV on the central nervous system.
Dr. Hsu received her Bsc(Med) MBBS medical degree from UNSW, Sydney, Australia with first class honor. She trained in internal medicine and completed fellowships in Clinical Immunology and Allergy, and Immunopathology at the Sydney South West Area Health Service, Australia. Dr. Hsu received her Ph.D from UNSW, Sydney Australia. Her Ph.D research focused on restoration of antigen specific CD4 T cell responses in advanced HIV infection. Her post-doctoral fellowship at the National Institute of Allergy and Infectious Diseases (NIAID) focused on immune perturbations in HIV infection including the pathogenesis of immune reconstitution inflammatory syndrome (IRIS) and persistent immune activation.
Hsu DC et al. "Impact of analytical treatment interruption on the central nervous system in a simian-HIV model." AIDS. 2019 Dec 1;33 Suppl 2:S189-S196. doi: 10.1097/QAD.0000000000002270.
Hsu DC et al. "Central nervous system inflammation and infection during early, non-accelerated Simian-Human Immunodeficiency Virus infection in rhesus macaques." Journal of Virology. 2018. doi: 10.1128/JVI.00222-18.
Hsu DC et al. "CD4+ Cell infiltration into subcutaneous adipose tissue is not indicative of productively infected cells during acute SHIV infection." J Med Primatol. 2017;46(4):154-157.
Hsu DC, Ananworanich J. "Immune interventions to eliminate the HIV reservoir." Curr Top Microbiol Immunol. 2017. doi: 10.1007/82_2017_70.