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HIV Research


MHRP is partnering with the Makerere University Walter Reed Project (MUWRP) in Uganda to conduct a novel HIV vaccine study called “RapidVax,” which recently started in March 2024. This study (RV591) combines experimental HIV vaccines with a novel dose escalation strategy with the goal of improving the body’s immune response.

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    MHRP's acute HIV infection (AHI) cohorts provide insight into critical early days after infection. These MHRP-led studies continue to expand the field’s knowledge of immune responses in acute infection, expose mechanisms for treatment and cure, and inform rational design of vaccines and other interventions.

  • Monoclonal Antibodies

    Identification and development of broadly neutralizing monoclonal antibodies (mAbs) is an exciting avenue to explore as a tool to both prevent HIV infection and as a therapy in HIV cure strategies. 

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    MHRP's Department of Epidemiology and Threat Assessment conducts research on the epidemiology of HIV and other infectious diseases that threaten the readiness of U.S. and allied military forces. This research informs countermeasure development, and policy development and public health practices to decrease the rates of HIV and other STIs in the military.