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October 28, 2020
Regular Cervical Cancer Screenings Improve Early Detection of Precancerous Lesions

Each year in Tanzania, 51 of every 100,000 women die from cervical cancer.  With limited access to cervical cancer screenings and treatment services, only around 20% of those with the disease will survive after 5 years of diagnosis. Women living with HIV are at a higher risk of getting the disease. They are also at a higher risk of the disease progressing to a more severe form as well as...

October 27, 2020
DREAMS Program Celebrates First Ever Graduation in Mbeya, Tanzania

Thousands of voices joined together in song as MHRP partners in Mbeya City, Tanzania, hosted the first ever DREAMS program graduation, where 1,804 adolescent girls and young women (AGYW) celebrated their completion of the core DREAMS training.   

The DREAMS initiative is funded by the U.S. President’s Emergency Plan for AIDS Relief (PEPFAR) and implemented through the Henry...

October 8, 2020
Army-developed Adjuvant, ALF, Shows Promising Results in SHIV Study

 In a new preclinical study conducted by MHRP, an HIV vaccine formulated with a novel adjuvant called AFLA developed at the Walter Reed Army Institute of Research elicited stronger immune responses than a vaccine with a more commonly used alum adjuvant. Findings from the study were published in PLOS Pathogens.

Researchers immunized rhesus macaques with a prime-boost HIV-1 vaccine...

July 6, 2020
MHRP and Collaborators at AIDS 2020 Virtual Conference

Oral Presentations: 

Julie Ake, Weight Gain and Hyperglycemia during the Dolutegravir Transition in Africa Sandhya Vasan (session moderator), HIV Vaccine Development: How to Forge Ahead  Sandhya Vasan (session moderator), HIV Cure: The Science, Ethics and Beyond Holly Peay, (RTI International), Is reluctance to restart ART a risk of ATI trials?

Other events of note

July 2, 2020
LTC(P) Julie Ake Named New Director of MHRP

We are pleased to announce that LTC(P) Julie Ake has been selected as the next Director of the U.S. Military HIV Research Program (MHRP), effective June 30. LTC(P) Ake has been with MHRP at the Walter Reed Army Institute of Research since 2010 and has served as the Principal Deputy Director for MHRP the last three years. Most recently, she has also been serving as WRAIR’s Deputy Principal for...

May 27, 2020
DREAMS Helps One Couple Find a Brighter Future

Mohammed Said is not hesitant to talk about his past as a drug addict and trafficker. Soft spoken and articulate, he cheerfully smiles as he narrates his recovery journey and how he met Rehema, the girl of his dreams.

Now 36, Mohammed was only 14 when he was introduced to a life of smuggling and dealing drugs. It was a dream come true when his parents agreed to let him travel outside...

February 6, 2020
MHRP Study Defining HIV Eclipse Phase Allows for More Accurate Estimate of Infection Timing

A new MHRP study shows the eclipse phase between HIV infection and earliest diagnosis via RNA testing lasted about a week, based on molecular dating and viral load growth rates obtained from one of its acute infection cohorts. The results were published this week in PLOS Pathogens.

“Individuals living with HIV rarely know when they became infected, but precise infection timing would...

January 14, 2020
New Study Reveals How Specialized Antimicrobial Human T Cells Respond in Acute HIV Infection

A new study led by MHRP has shown that a subset of T cells called mucosa-associated invariant T (MAIT) cells respond dynamically during acute HIV, and the functionality of these cells changes as infection progresses to become more innate-like. Findings were published today in Nature Communications.

MAIT cells are found abundantly in mucosal tissues, blood and the liver. MAIT cells...

December 23, 2019
MHRP's Top Highlights of 2019

MHRP is counting down the top five program highlights of the year in the areas of HIV vaccine development, cure research and global health promotion. Check back each day as we count down to number one:

MHRP’s partner sites in Uganda, Kenya and Tanzania have enrolled more than 65,000 young women in PEPFAR’s DREAMS public-partnership initiatives. This program aims to keep them...

December 2, 2019
World AIDS Day Event Highlights DoD Contributions to Fight the HIV Pandemic

The Walter Reed Army Institute of Research (WRAIR) hosted a World AIDS Day event Tuesday highlighting advances in DoD-led HIV research and celebrating the 10th anniversary of the Army-led RV144 HIV vaccine study. 

MHRP headed the RV144 “Thai study,” the first-ever – and only to-date – clinical trial to demonstrate an HIV vaccine regimen was safe and modestly effective in preventing HIV...