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January 17, 2019
Landmark Acute HIV Infection Cohort Study Concludes
MHRP’s RV217, an ambitious early capture acute HIV infection cohort study led by Clinical Deputy Director Dr. Merlin Robb, concluded in late 2018 after nine years of research activity.
The study, sponsored by the Division of AIDS at the National Institute of Allergy and Infectious Diseases, began in 2009 and prospectively followed a group of high-risk volunteers in East Africa and...
November 28, 2018
World AIDS Day 2018
The Walter Reed Army Institute of Research (WRAIR) is a critical partner in the whole of government approach to combat HIV—the most devastating pandemic of our time.
As the global AIDS epidemic has unfolded over the last 36 years, it’s become clear that the impact of HIV is closely tied to global security, regional stability, humanitarian concerns, counterterrorism, and peacekeeping...
October 16, 2018
MHRP and Collaborators at HIV Research for Prevention (HIVR4P) 2018
MHRP researchers and collaborators are scheduled to speak and present at the 2018 HIVR4P conference taking place October 23-25 in Madrid.
August 20, 2018
MHRP at the 2018 Military Health System Research Symposium
MHRP researchers and collaborators will be at this week's Military Health System Research Symposium in Florida, presenting abstracts on topics ranging from the AFRICOS cohort study to Zika vaccine studies.
CPT Suzanne Mate, MHSRS-18-1753: Joint West Africa Research Group is a MIL-MIL and MIL-CIV Global Health Engagement that delivers front-line biosurveillance technologies to West Africa...August 16, 2018
Study of Severe Infectious Diseases Enrolls 100th Volunteer
JWARG’s RV466 research protocol, a study designed to identify and characterize cases of suspected severe infectious disease, reached a key milestone in August with the enrollment of its 100th volunteer.
This multi-site protocol led by the U.S. Military HIV Research Program opened in Nigeria late last year and has now been activated at sites in Liberia and Ghana as well.
The...
July 20, 2018
MHRP Scientists and Collaborators Presenting at AIDS 2018 Conference
MHRP and collaborators will give the following presentations at the AIDS 2018 scientific meeting taking place July 23-27 in Amsterdam (bolded items are presentations or abstracts from MHRP researchers):
Monday, July 23
Jintanat Ananworanich, HIV Cure Research with the Community Workshop*
Tuesday, July 24
Jintanat Ananworanich, "Strategies for diagnosing and managing...
June 19, 2018
HIV Viral Load Rebounds Rapidly After Treatment Interruption in Individuals Who Begin ART During Fiebig I
HIV viral load rebounds rapidly despite suppressive antiretroviral therapy (ART) initiated at the earliest stage of infection before seroconversion. These findings were reported in the journal Nature Medicine by researchers at MHRP and SEARCH Thailand.
HIV latent reservoirs can hide from the immune system and pose a major obstacle to HIV remission. HIV remission is the ability to...
May 23, 2018
New HIV Cohort Study Opens In Germany
This week MHRP and collaborators at the Institute for HIV Research, University Duisburg-Essen launched a longitudinal cohort study in Germany to evaluate the incidence of HIV subtype B among an at-risk subpopulation and determine the feasibility of conducting an HIV vaccine efficacy trial there in the future. In addition, the study is the largest systematic epidemiological study for sexual...
May 17, 2018
Biomarker Signatures in Acute HIV Infection Associate with Viral Dynamics and Reservoir Size
Distinct biomarker signatures arising during acute HIV infection appear to be associated with the establishment and persistence of the viral reservoir, according to findings from a new study from MHRP published today in JCI Insight.
The viral reservoir poses a challenge in the quest to cure HIV infection since it contains cells in which HIV can lie dormant for many years, thereby...
May 16, 2018
Navigating the Path to an HIV Vaccine
In medical research, the breakthroughs get all the glory. Discoveries of new germs, vaccines and wonder drugs win scientists attention from the media and mentions in history books, building an illusion that medical progress leapfrogs from one “eureka moment” to the next.
But in reality, science is an arduous journey, an incremental process of inquiry and experimentation carried out by...