A new study led by the U.S. Military HIV Research Program (MHRP) has shown that active HIV reservoir that persists even during suppressive antiretroviral therapy (ART) is correlated with increased HIV-specific CD8+ T cell immune response, but prevents them from becoming fully functional. This suggests that strategies targeting the active HIV reservoir hold promise for functional “cure” therapies to bring about long-term HIV remission. Findings were published this week in Cell Host & Microbe.
MHRP in Nigeria, known locally as the Walter Reed Program-Nigeria (WRP-N), in partnership with the Nigeria Ministry of Defence Health Implementation Programme (NMODHIP), conducted a 3-day cervical cancer screening training for 28 healthcare professionals in April.
Dr. Trevor Crowell, a senior HJF clinical investigator with the U.S. Military HIV Research Program (MHRP) was awarded a three-year NIH R01 grant to leverage four MHRP cohorts to apply advanced machine learning analytic techniques to investigate COVID-19 vaccine uptake and impact on HIV and neurobehavioral outcomes.
As part of MHRP’s ongoing African Cohort Study (AFRICOS), researchers assessed the prevalence and incidence of HIV-TB among participants receiving services supported by the President’s Emergency Plan for AIDS Relief (PEPFAR) to identify factors associated with co-morbidity and better understand gaps in TB screening and diagnosis.
The 2023 Conference on Retroviruses and Opportunistic Infections (CROI) will kick off on February 19 in Seattle, Washington. Check out MHRP and collaborators at CROI.