Dr. Donn Colby is a Research Physician at the U.S. Military HIV Research Program (MHRP). Based in Seattle, WA, he supervises collaborative studies with Joint Base Lewis-McChord (JBLM) in Washington State and contributes to clinical protocols implemented in Asia. Prior to joining MHRP in 2019, he was co-investigator on the RV254 trial of acute HIV infection and the project lead on a number of clinical trials implemented in collaboration with MHRP at the Thai Red Cross AIDS Research Centre in Bangkok, Thailand.
Dr. Colby received his B.A. in Biology at Johns Hopkins University and his M.D. at the State University of New York at Stony Brook. He did his internal medicine residency training and Masters in Public Health at the University of Washington in Seattle. In 2001 he received a Fulbright Scholarship to study the epidemiology of HIV in Vietnam, leading to over two decades of collaborative work in Southeast Asia. He was voted Distinguished Alumni of the year by the University of Washington School of Public Health in 2006.
Dr. Colby’s has published extensively on the epidemiology of HIV in Southeast Asia, clinical outcomes among people living with HIV, the implementation of preexposure prophylaxis (PrEP), and clinical trials of novel therapeutics investigating the potential to cure HIV infection. He is also a member of the AIDS Clinical Trials Group (ACTG), HIV Reservoirs and Viral Eradication (Cure) Transformative Science Group and an academic editor for PLoS One.
Colby DJ, Sarnecki M, Barouch DH, Tipsuk S, Stieh DJ, Kroon E, Schuetz A, Intasan J, Sacdalan C, Pinyakorn S, Grandin P, Song H, Tovanabutra S, Shubin Z, Kim D, Paquin-Proulx D, Eller MA, Thomas R, de Souza M, Wieczorek L, Polonis VR, Pagliuzza A, Chomont N, Peter L, Nkolola JP, Vingerhoets J, Truyers C, Pau MG, Schuitemaker H, Phanuphak N, Michael N, Robb ML, Tomaka FL, Ananworanich J. Safety and immunogenicity of Ad26 and MVA vaccines in acutely treated HIV and effect on viral rebound after antiretroviral therapy interruption. Nat Med. 2020 Apr;26(4):498-501.
Han WM, Colby DJ, Khlaiphuengsin A, Apornpong T, Kerr SJ, Ubolyam S, Kroon E, Phanuphak N, Vasan S, Matthews GV, Avihingsanon A, Ruxrungtham K, Phanuphak P, Tangkijvanich P. Large transmission cluster of acute hepatitis C identified among HIV-positive men who have sex with men in Bangkok, Thailand. Liver Int. 2020 Sep;40(9):2104-2109.
Wansom T, Pinyakorn S, Kolsteeg CJ, Kroon E, Sacdalan CP, Chomchey N, Ananworanich J, Vasan S, Phanuphak N, Colby DJ. Group Sex and Methamphetamine Use Fuel an Explosive Epidemic of Hepatitis C Among HIV-Infected Men Who Have Sex With Men in Bangkok, Thailand. J Acquir Immune Defic Syndr. 2020 Aug 1;84(4):331-335.
Crowell TA, Colby DJ, Pinyakorn S, Sacdalan C, Pagliuzza A, Intasan J, Benjapornpong K, Tangnaree K, Chomchey N, Kroon E, de Souza MS, Tovanabutra S, Rolland M, Eller MA, Paquin-Proulx D, Bolton DL, Tokarev A, Thomas R, Takata H, Trautmann L, Krebs SJ, Modjarrad K, McDermott AB, Bailer RT, Doria-Rose N, Patel B, Gorelick RJ, Fullmer BA, Schuetz A, Grandin PV, O'Connell RJ, Ledgerwood JE, Graham BS, Tressler R, Mascola JR, Chomont N, Michael NL, Robb ML, Phanuphak N, Ananworanich J. Safety and efficacy of VRC01 broadly neutralising antibodies in adults with acutely treated HIV (RV397): a phase 2, randomised, double-blind, placebo-controlled trial. Lancet HIV. 2019 May;6(5):e297-e306.
Colby DJ, Kroon E, Sacdalan C, Gandhi M, Grant RM, Phanuphak P, Ananworanich J, Robb ML, Phanuphak N. Acquisition of Multidrug-Resistant Human Immunodeficiency Virus Type 1 Infection in a Patient Taking Preexposure Prophylaxis. Clin Infect Dis. 2018 Aug 31;67(6):962-964.
Colby DJ, Posuwan N, Kroon E, Phanuphak N, Ananworanich J, Robb ML, Phanuphak P, Poovorawan Y. Reply to Chen et al: Acute hepatitis A among HIV-infected Thai MSM is linked to outbreaks in Taiwan and Europe. J Infect Dis. 2018 Jul 2;218(3):505-507.
Colby DJ, Trautmann L, Pinyakorn S, Leyre L, Pagliuzza A, Kroon E, Rolland M, Takata H, Buranapraditkun S, Intasan J, Chomchey N, Muir R, Haddad EK, Tovanabutra S, Ubolyam S, Bolton DL, Fullmer BA, Gorelick RJ, Fox L, Crowell TA, Trichavaroj R, O'Connell R, Chomont N, Kim JH, Michael NL, Robb ML, Phanuphak N, Ananworanich J. Rapid HIV RNA rebound after antiretroviral treatment interruption in persons durably suppressed in Fiebig I acute HIV infection. Nat Med. 2018 Jul;24(7):923-926.
Crowell TA, Colby DJ, Pinyakorn S, Fletcher JLK, Kroon E, Schuetz A, Krebs SJ, Slike BM, Leyre L, Chomont N, Jagodzinski LL, Sereti I, Utay NS, Dewar R, Rerknimitr R, Chomchey N, Trichavaroj R, Valcour VG, Spudich S, Michael NL, Robb ML, Phanuphak N, Ananworanich J. Acute Retroviral Syndrome Is Associated With High Viral Burden, CD4 Depletion, and Immune Activation in Systemic and Tissue Compartments. Clin Infect Dis. 2018 May 2;66(10):1540-1549.
Colby DJ, Crowell TA, Sirivichayakul S, Pinyakorn S, Kroon E, Benjapornpong K, Intasan J, Trichavaroj R, Tovanabutra S, Robb M, Phanuphak P, Ananworanich J, Phanuphak N. Declining trend in transmitted drug resistance detected in a prospective cohort study of acute HIV infection in Bangkok, Thailand. J Int AIDS Soc. 2016;19(1):20966.
Colby DJ, Oldenburg CE, Nguyen T, Closson EF, Biello KB, Mayer KH, Mimiaga MJ. HIV, Hepatitis C, and Other Sexually Transmitted Infections Among Male Sex Workers in Ho Chi Minh City, Vietnam. AIDS Behav. 2016 Apr;20(4):768-75.
Complete list of published work: